Deep-well Plates (V)

Deep-well plates, often referred to as deep-well microplates or simply deep plates, are a type of laboratory equipment commonly used in various scientific and biotechnological applications. These plates are typically made of plastic and are designed with a grid of multiple wells or reservoirs, arranged in a 2D format, where each well can hold a specific volume of liquid. The "deep" in deep-well plates refers to the relatively tall and cylindrical shape of the wells, which allows them to hold larger volumes of liquid compared to standard microplates with shallow wells.
Key features and uses of deep-well plates (often indicated as "V" for volume) include:
High Sample Volume: Deep-well plates are designed to hold larger sample volumes, typically ranging from 0.5 mL to 2 mL per well, although other sizes are available. This makes them suitable for applications that require significant sample storage, such as sample preparation, serial dilutions, and various biochemical assays.
Liquid Handling: Deep-well plates are compatible with various liquid-handling equipment, such as pipettors, automated liquid handlers, and robotic systems. This compatibility allows for high-throughput screening and sample processing.
Sample Storage: Deep-well plates are commonly used for storing samples, reagents, or compounds in biorepositories, clinical laboratories, and research settings. Their well-sealed design helps prevent cross-contamination and sample loss.
Assays: Deep-well plates are frequently employed for running a wide range of assays, including enzyme-linked immunosorbent assays (ELISAs), polymerase chain reactions (PCRs), and cell culture experiments. The high sample volume capacity is especially useful for mixing reagents and conducting multiple reactions simultaneously.
Temperature Control: Some deep-well plates are designed to be compatible with temperature-controlled equipment, such as thermocyclers, allowing for precise temperature regulation during assays like PCR.
Automation: Deep-well plates are often utilized in high-throughput screening and automation workflows due to their compatibility with robotic systems. They can streamline processes in drug discovery, genomics, and other research areas.
Versatility: Deep-well plates come in various formats, including 96-well and 384-well plates, with different well geometries. This versatility allows researchers to choose the format that best suits their specific needs.
Deep-well plates are available from numerous manufacturers and can be made from different materials, such as polypropylene or polystyrene. The choice of material may depend on the compatibility with the intended applications, such as chemical resistance, sterilization methods, and optical properties for assays that require fluorescence or absorbance measurements.
In summary, deep-well plates are a valuable tool in laboratories and research environments for the efficient handling, storage, and analysis of samples, making them indispensable in a wide range of scientific and biotechnological applications.

• Sample storage
• Compound screening
• Protein crystallization