How does the pore size of Filtered Pipette Tips affect sample processing efficiency?

Filtered Pipette Tips play a vital role in laboratory sample processing, and their pore size has a profound impact on sample processing efficiency in many aspects.
Smaller pore sizes, such as 0.2 microns, can effectively block tiny impurity particles, bacteria, viruses and other contaminants from entering the pipette. When processing biological samples, such as cell culture fluid and nucleic acid samples, this can ensure the purity of the sample and prevent impurities from interfering with subsequent experimental results. Because once these tiny contaminants enter the sample, they may affect the growth state of the cell, cause false positive or false negative results in nucleic acid testing, etc. However, smaller pore sizes may encounter resistance when aspirating some samples containing macromolecules or high viscosity, reducing the aspiration speed and thus affecting the overall sample processing efficiency. For example, when processing samples containing a large amount of protein polymers, too fine a pore size may cause the protein to adsorb on the filter membrane, causing the pipette tip to be blocked, requiring frequent replacement of the pipette tip, and consuming time and resources.
On the contrary, a larger filter pore size, such as 5 microns, is more advantageous for some relatively pure samples that only require preliminary filtration. It can quickly absorb samples, reduce the absorption time, and increase the processing throughput. In large-scale sample screening experiments, if there are fewer impurities in the sample, a larger pore filter tip allows the operator to process more samples per unit time. However, this larger pore tip has a poor filtering effect on tiny pollutants and may not meet the needs in experiments with extremely high sample purity requirements.
The selection of a suitable filter pore size depends on the specific experimental requirements and sample characteristics. If a high-precision genetic testing experiment is being conducted, a smaller pore filter tip may be the first choice; while in the preliminary detection of some industrial microbial fermentation broths, a larger pore tip may be more suitable. Our company provides filter pipette tips with a variety of filter pore size specifications, which can meet the diverse needs of sample processing in different laboratories. With its high-quality filter membrane material and precise pore size control, it effectively improves your sample processing efficiency and experimental accuracy.